STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Igag_0143Hypothetical protein. (159 aa)    
Predicted Functional Partners:
Igag_1096
Hypothetical protein; KEGG: dka:DKAM_1337 phosphoesterase, RecJ domain protein.
    
 
 0.755
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
     
 0.746
pcn-2
Proliferating cell nuclear antigen PcnA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
  
  
 0.721
Igag_1496
Protein of unknown function DUF1288; InterPro IPR010709; KEGG: smr:Smar_1226 hypothetical protein; PFAM: Protein of unknown function DUF1288; SPTR: A3DNW0 Putative uncharacterized protein.
    
 
 0.675
rpl44e
LSU ribosomal protein L44E; Binds to the 23S rRNA.
  
    0.552
rps27e
COGs: COG2051 Ribosomal protein S27E; InterPro IPR000592; KEGG: sso:SSO7114 30S ribosomal protein S27e; PFAM: Ribosomal protein S27E; SPTR: Q97Z80 30S ribosomal protein S27e; PFAM: Ribosomal protein S27.
       0.475
Igag_0146
KEGG: ape:APE_1804 hypothetical protein; SPTR: Q9YAZ1 Uncharacterized protein APE_1804.
       0.467
nop10
RNA-binding protein Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
       0.414
Igag_0140
COGs: COG1093 Translation initiation factor 2 alpha subunit (eIF-2alpha); InterPro IPR003029:IPR011488; KEGG: hbu:Hbut_1640 translation initiation factor IF-2 subunit alpha; PFAM: translation initiation factor 2, alpha subunit; RNA binding S1 domain protein; SPTR: A2BN93 Translation initiation factor 2 subunit alpha; PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain.
       0.414
Your Current Organism:
Ignisphaera aggregans
NCBI taxonomy Id: 583356
Other names: I. aggregans DSM 17230, Ignisphaera aggregans DSM 17230, Ignisphaera aggregans str. DSM 17230, Ignisphaera aggregans strain DSM 17230
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