STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Igag_0434Phosphomethylpyrimidine kinase; COGs: COG1992 conserved hypothetical protein; InterPro IPR019293; KEGG: hbu:Hbut_0125 transcriptional regulator; PFAM: Phosphomethylpyrimidine kinase; SPTR: A2BJ39 Predicted transcriptional regulator-conserved protein; PFAM: Archaeal phosphomethylpyrimidine kinase. (302 aa)    
Predicted Functional Partners:
Igag_1669
Phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR019293:IPR013749:IPR004399; KEGG: smr:Smar_0049 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; Phosphomethylpyrimidine kinase; SPTR: A3DKK2 Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase; Archaeal phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase.
 
  
0.588
Igag_1298
Hydroxymethylpyrimidine synthase; COGs: COG0422 Thiamine biosynthesis protein ThiC; InterPro IPR002817; KEGG: hbu:Hbut_0289 thiamine biosynthesis protein ThiC; PFAM: thiamine biosynthesis protein ThiC; SPTR: A2BJK0 Thiamine biosynthesis protein ThiC; TIGRFAM: thiamine biosynthesis protein ThiC; PFAM: ThiC family; TIGRFAM: thiamine biosynthesis protein ThiC.
    
 0.572
Igag_0436
Radical SAM domain protein; COGs: COG5014 Fe-S oxidoreductase; InterPro IPR007197; KEGG: tpe:Tpen_1582 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: A1S0J7 Radical SAM domain protein; PFAM: Radical SAM superfamily.
 
     0.560
Igag_1500
ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication.
  
     0.537
Igag_0700
KEGG: Hypothetical protein CBG08535; SPTR: B5ITE5 Putative uncharacterized protein.
  
     0.511
Igag_0435
Hypothetical protein.
       0.497
Igag_1012
Conserved hypothetical protein; COGs: COG1611 Rossmann fold nucleotide-binding protein; KEGG: sto:ST1847 hypothetical protein; SPTR: Q96ZI8 Putative uncharacterized protein ST1847; PFAM: Possible lysine decarboxylase; TIGRFAM: conserved hypothetical protein, DprA/Smf-related, family 1.
  
     0.492
Igag_0472
COGs: COG0704 Phosphate uptake regulator; InterPro IPR007159:IPR008170; KEGG: cma:Cmaq_1109 SpoVT/AbrB domain-containing protein; PFAM: PhoU family protein; SpoVT/AbrB domain protein; SPTR: A8MDT1 SpoVT/AbrB domain protein; PFAM: PhoU domain; SpoVT / AbrB like domain.
  
     0.467
Igag_0288
Conserved hypothetical protein; COGs: COG3357 transcriptional regulator protein; KEGG: sto:ST2144 hypothetical protein; SPTR: Q96YM8 Putative uncharacterized protein ST2144.
  
     0.462
Igag_1228
Protein of unknown function DUF343; InterPro IPR005651; KEGG: sto:ST0241 hypothetical protein; PFAM: protein of unknown function DUF343; SPTR: Q976E5 Putative uncharacterized protein ST0241; PFAM: Trm112p-like protein.
  
     0.461
Your Current Organism:
Ignisphaera aggregans
NCBI taxonomy Id: 583356
Other names: I. aggregans DSM 17230, Ignisphaera aggregans DSM 17230, Ignisphaera aggregans str. DSM 17230, Ignisphaera aggregans strain DSM 17230
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.