STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Igag_0522HEPN domain protein; InterPro IPR007842; KEGG: tpe:Tpen_1688 HEPN domain-containing protein; PFAM: HEPN domain protein; SMART: HEPN domain protein; SPTR: A1S0V3 HEPN domain protein; PFAM: HEPN domain. (138 aa)    
Predicted Functional Partners:
Igag_0523
InterPro IPR002934; KEGG: sso:SSO1884 hypothetical protein; PFAM: DNA polymerase beta domain protein region; SPTR: Q97X67 Putative uncharacterized protein; PFAM: Nucleotidyltransferase domain.
   
   0.822
Igag_0521
Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510:IPR006162; KEGG: dka:DKAM_0933 peptidase U62, modulator of DNA gyrase; PFAM: peptidase U62 modulator of DNA gyrase; SPTR: B8D578 Peptidase U62, modulator of DNA gyrase; PFAM: Putative modulator of DNA gyrase.
       0.532
Igag_0520
Protein of unknown function DUF998; COGs: COG3371 membrane protein; InterPro IPR009339; KEGG: sto:ST1539 hypothetical protein; PFAM: Protein of unknown function DUF998; SPTR: Q970R2 Putative uncharacterized protein ST1539; PFAM: Protein of unknown function (DUF998).
       0.426
Your Current Organism:
Ignisphaera aggregans
NCBI taxonomy Id: 583356
Other names: I. aggregans DSM 17230, Ignisphaera aggregans DSM 17230, Ignisphaera aggregans str. DSM 17230, Ignisphaera aggregans strain DSM 17230
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.