STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Experiments
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[Homology]
Score
Igag_0656Beta-ribofuranosylaminobenzene 5'-phosphate synthase family; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P). (318 aa)    
Predicted Functional Partners:
Igag_0281
Beta-ribofuranosylaminobenzene 5'-phosphate synthase family; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
  
  
 
0.914
Igag_0657
Conserved hypothetical protein; COGs: COG2441 butyrate kinase; KEGG: tko:TK2243 hypothetical protein; SPTR: Q5JHQ0 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1464).
 
     0.912
Igag_0280
Dihydropteroate synthase-related protein; COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR005236; KEGG: mth:MTH1741 hypothetical protein; PFAM: dihydropteroate synthase DHPS; SPTR: O27773 Conserved protein; TIGRFAM: dihydropteroate synthase-related protein; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase-related protein.
 
     0.755
Igag_1675
COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase; InterPro IPR002736; KEGG: smr:Smar_0395 triphosphoribosyl-dephospho-CoA protein; PFAM: triphosphoribosyl-dephospho-CoA protein; SPTR: A3DLJ7 Triphosphoribosyl-dephospho-CoA protein; PFAM: ATP:dephospho-CoA triphosphoribosyl transferase.
 
     0.739
Igag_0381
COGs: COG2218 Formylmethanofuran dehydrogenase subunit C; InterPro IPR002489:IPR017550; KEGG: mka:MK1530 formylmethanofuran dehydrogenase subunit C; PFAM: glutamate synthase alpha subunit domain protein; PRIAM: Formylmethanofuran dehydrogenase; SPTR: Q8TV68 Formylmethanofuran dehydrogenase subunit C; TIGRFAM: formylmethanofuran dehydrogenase subunit C; PFAM: GXGXG motif; TIGRFAM: formylmethanofuran dehydrogenase subunit C.
  
     0.713
Igag_0274
Formaldehyde-activating enzyme; COGs: COG1795 conserved hypothetical protein; InterPro IPR014826; KEGG: rba:RB10297 D-arabino 3-hexulose 6-phosphate formaldehyde lyase (hps-2); PFAM: Formaldehyde-activating enzyme (Fae); SPTR: Q7UF74 Probable D-arabino 3-hexulose 6-phosphate formaldehyde lyase (Hps-2); TIGRFAM: formaldehyde-activating enzyme; PFAM: Formaldehyde-activating enzyme (Fae); TIGRFAM: formaldehyde-activating enzyme.
  
     0.708
Igag_0279
Flavoprotein; COGs: COG1036 flavoprotein; InterPro IPR001450:IPR003382:IPR017900; KEGG: mja:MJ0208 4Fe-4S iron-sulfur protein; PFAM: flavoprotein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q57661 Uncharacterized protein MJ0208; PFAM: 4Fe-4S binding domain; Flavoprotein; TIGRFAM: archaeoflavoprotein, MJ0208 family.
 
    0.692
Igag_0382
COGs: COG1029 Formylmethanofuran dehydrogenase subunit B; InterPro IPR006656:IPR006657:IPR016457; KEGG: mka:MK0259 formylmethanofuran dehydrogenase subunit B; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase; SPTR: Q8TYN5 Formylmethanofuran dehydrogenase subunit B; TIGRFAM: formylmethanofuran dehydrogenase subunit B; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; TIGRFAM: formylmethanofuran dehydrogenase subunit B.
 
     0.585
Igag_0658
KEGG: tpe:Tpen_0008 hypothetical protein; SPTR: A1RW38 Putative uncharacterized protein.
       0.548
Igag_0277
Conserved hypothetical protein; COGs: COG2441 butyrate kinase; KEGG: hbu:Hbut_0767 hypothetical protein; SPTR: A2BKW0 Conserved archaeal protein; PFAM: Protein of unknown function (DUF1464).
 
     0.544
Your Current Organism:
Ignisphaera aggregans
NCBI taxonomy Id: 583356
Other names: I. aggregans DSM 17230, Ignisphaera aggregans DSM 17230, Ignisphaera aggregans str. DSM 17230, Ignisphaera aggregans strain DSM 17230
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