STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adeCOGs: COG1001 Adenine deaminase; InterPro IPR006680:IPR019775; KEGG: smr:Smar_0382 adenine deaminase; PFAM: amidohydrolase; PRIAM: Adenine deaminase; SPTR: A3DLI4 Adenine deaminase; PFAM: Amidohydrolase family; TIGRFAM: adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (613 aa)    
Predicted Functional Partners:
Igag_0463
Phosphoribosyltransferase; COGs: COG0503 Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein; InterPro IPR000836; KEGG: dka:DKAM_0532 adenine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: B8D427 Adenine phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain.
    
 0.920
Igag_0906
COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR001093:IPR000644:IPR002932; KEGG: cma:Cmaq_1624 malate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; ferredoxin-dependent glutamate synthase; PRIAM: IMP dehydrogenase; SMART: CBS domain containing protein; SPTR: A8M9X6 Malate dehydrogenase; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase.
  
  
 0.820
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.669
Igag_0904
COGs: COG1874 Beta-galactosidase; InterPro IPR001944:IPR013529:IPR002345; KEGG: cma:Cmaq_0900 beta-galactosidase; PFAM: glycoside hydrolase family 35; Glycoside hydrolase family 42 domain protein; PRIAM: Beta-galactosidase; SPTR: A8MD78 Beta-galactosidase; PFAM: Glycosyl hydrolases family 35; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type.
       0.459
Your Current Organism:
Ignisphaera aggregans
NCBI taxonomy Id: 583356
Other names: I. aggregans DSM 17230, Ignisphaera aggregans DSM 17230, Ignisphaera aggregans str. DSM 17230, Ignisphaera aggregans strain DSM 17230
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.