STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Igag_1095KEGG: mse:Msed_1883 hypothetical protein; PFAM: Transcription factor Pcc1. (85 aa)    
Predicted Functional Partners:
Igag_1096
Hypothetical protein; KEGG: dka:DKAM_1337 phosphoesterase, RecJ domain protein.
  
    0.813
rps15
COGs: COG0184 Ribosomal protein S15P/S13E; InterPro IPR012606:IPR000589; KEGG: smr:Smar_0841 30S ribosomal protein S15P; PFAM: Ribosomal S13S15 domain protein; ribosomal protein S15; SPTR: A3DMT2 30S ribosomal protein S15P/S13e; PFAM: Ribosomal S13/S15 N-terminal domain; Ribosomal protein S15.
       0.733
Igag_1098
dITPase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.632
Igag_1099
COGs: COG3642 Mn2+-dependent serine/threonine protein kinase; InterPro IPR018934:IPR002290:IPR008266:IPR000719; KEGG: sso:SSO0433 O-sialoglycoprotein endopeptidase; PFAM: RIO-like kinase; SMART: serine/threonine protein kinase; SPTR: Q97ZY9 O-sialoglycoprotein endopeptidase; PFAM: RIO1 family.
       0.632
kae1
Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family.
       0.632
rps3ae
COGs: COG1890 Ribosomal protein S3AE; InterPro IPR001593:IPR018281; KEGG: hbu:Hbut_0428 30S ribosomal protein S3Ae; PFAM: ribosomal protein S3Ae; SPTR: A2BJY3 30S ribosomal protein S3Ae; PFAM: Ribosomal S3Ae family; Belongs to the eukaryotic ribosomal protein eS1 family.
       0.605
rps27ae
SSU ribosomal protein S27AE; InterPro IPR002906; KEGG: hbu:Hbut_0435 30S ribosomal protein S27AE; PFAM: Ribosomal protein S27a; SPTR: A2BJZ0 30S ribosomal protein S27ae; PFAM: Ribosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family.
       0.499
rps24e
COGs: COG2004 Ribosomal protein S24E; InterPro IPR001976; KEGG: tpe:Tpen_0448 ribosomal protein S24e; SPTR: A1RXC7 SSU ribosomal protein S24E; PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.
       0.483
spt4
DNA-directed RNA polymerase, subunit E'; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
       0.438
Igag_1093
Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR001451:IPR005835; KEGG: smr:Smar_0849 nucleotidyl transferase; PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; SPTR: A3DMT9 Nucleotidyl transferase; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylylransferase, long form.
       0.401
Your Current Organism:
Ignisphaera aggregans
NCBI taxonomy Id: 583356
Other names: I. aggregans DSM 17230, Ignisphaera aggregans DSM 17230, Ignisphaera aggregans str. DSM 17230, Ignisphaera aggregans strain DSM 17230
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