STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Igag_1383RNA polymerase Rbp10; InterPro IPR006591; KEGG: sai:Saci_0864 DNA-directed RNA polymerase subunit P; SMART: RNA polymerase Rbp10; SPTR: Q4JAE8 DNA-directed RNA polymerase subunit P; PFAM: DNA directed RNA polymerase, 7 kDa subunit. (48 aa)    
Predicted Functional Partners:
rpoN
DNA-directed RNA polymerase, subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.
   
 0.998
rpoK
DNA-directed RNA polymerase, subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.
   
 0.998
rpoH
DNA-directed RNA polymerase, subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
   
 0.998
Igag_0193
COGs: COG0202 DNA-directed RNA polymerase alpha subunit/40 kD subunit; InterProIPR001450:IPR011262:IPR011261:IPR011263:IPR 001514:IPR017900; KEGG: smr:Smar_0815 DNA-directed RNA polymerase, subunit D; PFAM: RNA polymerase insert; 4Fe-4S ferredoxin iron-sulfur binding domain protein; RNA polymerase dimerisation; SMART: RNA polymerase RpoA/D/Rpb3-type; SPTR: A3DMQ6 DNA-directed RNA polymerase, subunit D; PFAM: RNA polymerase Rpb3/Rpb11 dimerisation domain; RNA polymerase Rpb3/RpoA insert domain.
   
 0.997
Igag_1245
DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.997
Igag_0212
COGs: COG1095 DNA-directed RNA polymerase subunit E'; InterPro IPR003029:IPR005576:IPR004519; KEGG: sso:SSO0415 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7 domain protein; RNA binding S1 domain protein; PRIAM: DNA-directed RNA polymerase; SPTR: Q980A3 DNA-directed RNA polymerase, subunit E' (RpoE1); TIGRFAM: DNA-directed RNA polymerase; PFAM: S1 RNA binding domain; RNA polymerase Rpb7-like, N-terminal domain; TIGRFAM: DNA-directed RNA polymerase (rpoE), archaeal and eukaryotic form.
   
 0.988
Igag_1052
RNA polymerase dimerisation; InterPro IPR011261; KEGG: hbu:Hbut_1648 DNA-directed RNA polymerase subunit L; PFAM: RNA polymerase dimerisation; SPTR: A2BNA1 DNA-directed RNA polymerase subunit L.
   
 0.984
Igag_1058
Type III restriction protein res subunit; COGs: COG1061 DNA or RNA helicase of superfamily II; InterProIPR000330:IPR011545:IPR001650:IPR006935:IPR 014001:IPR014021; KEGG: sto:ST1287 hypothetical protein; PFAM: type III restriction protein res subunit; helicase domain protein; DEAD/DEAH box helicase domain protein; SNF2-related protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Q971U1 Putative uncharacterized protein ST1287; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit.
    
  0.969
tfe
Transcription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongatio [...]
    
 0.967
rpl40e
LSU ribosomal protein L40E; InterPro IPR001975; KEGG: ape:APE_0113a 50S ribosomal protein L40e; PFAM: Ribosomal protein L40e; SPTR: Q9YFY7 50S ribosomal protein L40e; PFAM: Ribosomal L40e family; Belongs to the eukaryotic ribosomal protein eL40 family.
   
  0.956
Your Current Organism:
Ignisphaera aggregans
NCBI taxonomy Id: 583356
Other names: I. aggregans DSM 17230, Ignisphaera aggregans DSM 17230, Ignisphaera aggregans str. DSM 17230, Ignisphaera aggregans strain DSM 17230
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