STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Igag_1534KEGG: sto:ST1246 hypothetical protein; SPTR: Q971Y2 Putative uncharacterized protein ST1246. (213 aa)    
Predicted Functional Partners:
Igag_1535
hydroxymethylglutaryl-CoA reductase, degradative; COGs: COG1257 Hydroxymethylglutaryl-CoA reductase; InterPro IPR002202:IPR004553; KEGG: smr:Smar_0178 hydroxymethylglutaryl-CoA reductase, degradative; PRIAM: Hydroxymethylglutaryl-CoA reductase; SPTR: A3DKY1 Hydroxymethylglutaryl-CoA reductase, degradative; TIGRFAM: hydroxymethylglutaryl-CoA reductase, degradative; PFAM: Hydroxymethylglutaryl-coenzyme A reductase; TIGRFAM: hydroxymethylglutaryl-CoA reductase, degradative; Belongs to the HMG-CoA reductase family.
       0.621
Igag_1349
COGs: COG2522 transcriptional regulator protein; KEGG: smr:Smar_0682 transcriptional regulator-like protein; SPTR: A3DMC6 Transcriptional regulator-like protein; PFAM: Helix-turn-helix.
  
     0.595
Igag_1834
COGs: COG2112 Ser/Thr protein kinase; InterPro IPR000719; KEGG: nmr:Nmar_1783 putative serine/threonine protein kinase; SPTR: A9A3X9 Putative serine/threonine protein kinase.
  
     0.569
Igag_1533
COGs: COG2872 metal-dependent hydrolase related to alanyl-tRNA synthetase HxxxH domain; InterPro IPR012947:IPR018165; KEGG: smr:Smar_1138 Ala-tRNA(Pro) hydrolase; PFAM: Threonyl/alanyl tRNA synthetase SAD; SPTR: A3DNM3 Ala-tRNA(Pro) hydrolase; PFAM: Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetases class II (A).
       0.536
Igag_1536
Protein of unknown function DUF434; COGs: COG2454 conserved hypothetical protein; InterPro IPR007368; KEGG: sto:ST1363 hypothetical protein; PFAM: protein of unknown function DUF434; SPTR: Q971J5 Putative uncharacterized protein ST1363; PFAM: Protein of unknown function (DUF434).
       0.510
Igag_0474
Protein of unknown function UPF0147; COGs: COG1698 conserved hypothetical protein; InterPro IPR005354; KEGG: hbu:Hbut_1631 hypothetical protein; PFAM: Protein of unknown function UPF0147; SPTR: A2BN84 Conserved archaeal protein; PFAM: Uncharacterised protein family (UPF0147); Belongs to the UPF0147 family.
  
     0.486
Igag_1815
InterPro IPR005651; KEGG: sin:YN1551_0868 protein of unknown function DUF343; PFAM: protein of unknown function DUF343; SPTR: C4KIX5 Putative uncharacterized protein; PFAM: Trm112p-like protein.
  
     0.442
Igag_0337
Protein of unknown function DUF1512; COGs: COG4046 conserved hypothetical protein; InterPro IPR009995; KEGG: ape:APE_1123.1 hypothetical protein; PFAM: Protein of unknown function DUF1512; SPTR: Q9YCY9 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1512).
  
     0.436
Igag_0249
InterPro IPR004130; KEGG: hbu:Hbut_1433 GTPase; PFAM: protein of unknown function ATP binding; SPTR: A2BMP6 Conserved hypothetical ATP binding protein; PFAM: Conserved hypothetical ATP binding protein.
  
     0.412
Igag_0487
CDP-alcohol phosphatidyltransferase; COGs: COG1213 sugar nucleotidyltransferase; InterPro IPR000462; KEGG: kcr:Kcr_0184 CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: B1L3B5 CDP-alcohol phosphatidyltransferase; PFAM: Nucleotidyl transferase; CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
     0.412
Your Current Organism:
Ignisphaera aggregans
NCBI taxonomy Id: 583356
Other names: I. aggregans DSM 17230, Ignisphaera aggregans DSM 17230, Ignisphaera aggregans str. DSM 17230, Ignisphaera aggregans strain DSM 17230
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