STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
rbcLRibulose 1,5-bisphosphate carboxylase large subunit; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (444 aa)    
Predicted Functional Partners:
Igag_1626
COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR006380:IPR005834:IPR013200:IPR006382; KEGG: sai:Saci_1518 hypothetical protein; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase; PRIAM: Phosphoglycolate phosphatase; SPTR: Q4J8P4 Phosphoglycolate phosphatase; TIGRFAM: SPP-like hydrolase; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; sucrose-phosphate phosphatase-like hydrolase, Archaeal.
    
  0.952
Igag_0413
COGs: COG0561 hydrolase of the HAD superfamily; InterProIPR006380:IPR005834:IPR013200:IPR006382:IPR 006379; KEGG: hbu:Hbut_0505 phosphoglycolate phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase; PRIAM: Phosphoglycolate phosphatase; SPTR: A2BK56 Phosphoglycolate phosphatase; TIGRFAM: SPP-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; sucrose-phosphate phosphatase-like hydro [...]
     
  0.900
Igag_1623
Class II aldolase/adducin family protein; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: cma:Cmaq_1697 class II aldolase/adducin family protein; PFAM: class II aldolase/adducin family protein; SPTR: A8MAE3 Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain.
  
  
 0.633
Igag_0059
Translation initiation factor 2B subunit I family (IF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
  
  
 0.569
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
      
 0.511
Igag_1282
Class II aldolase/adducin family protein; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: cma:Cmaq_0711 class II aldolase/adducin family protein; PFAM: class II aldolase/adducin family protein; SPTR: A8MCP1 Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase.
  
  
 0.502
Igag_1569
Class II aldolase/adducin family protein; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: cma:Cmaq_0711 class II aldolase/adducin family protein; PFAM: class II aldolase/adducin family protein; SPTR: A8MCP1 Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain.
  
  
 0.502
Igag_1624
Rhamnulokinase; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: cma:Cmaq_0709 carbohydrate kinase FGGY; PFAM: Carbohydrate kinase, FGGY-like; PRIAM: Rhamnulokinase; SPTR: A8MCN9 Carbohydrate kinase FGGY; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain.
       0.479
Igag_1621
InterPro IPR012307; KEGG: dtu:Dtur_0423 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain protein TIM barrel; SPTR: B8E1U3 Xylose isomerase domain protein TIM barrel.
 
     0.416
Igag_0399
KEGG: cma:Cmaq_0827 hypothetical protein; SPTR: A8MD06 Putative uncharacterized protein.
   
    0.414
Your Current Organism:
Ignisphaera aggregans
NCBI taxonomy Id: 583356
Other names: I. aggregans DSM 17230, Ignisphaera aggregans DSM 17230, Ignisphaera aggregans str. DSM 17230, Ignisphaera aggregans strain DSM 17230
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