STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Igag_1709COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500; KEGG: dka:DKAM_1397 sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; SPTR: B8D6J2 Sugar-phosphate isomerase, RpiB/LacA/LacB family; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/Galactose Isomerase; TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family. (158 aa)    
Predicted Functional Partners:
Igag_0008
Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836:IPR005946; KEGG: sto:ST0946 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Q973F3 Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase.
    
 0.935
Igag_1730
COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR005476:IPR005475; KEGG: sto:ST2269 transketolase; PFAM: Transketolase central region; Transketolase domain protein; SPTR: Q96Y99 313aa long hypothetical transketolase; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
  
 
 0.930
Igag_0051
COGs: COG0120 Ribose 5-phosphate isomerase; InterPro IPR004788:IPR017441; KEGG: cma:Cmaq_0742 ribose 5-phosphate isomerase; PFAM: Ribose 5-phosphate isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: A8MCS2 Ribose 5-phosphate isomerase; TIGRFAM: ribose 5-phosphate isomerase; PFAM: Ribose 5-phosphate isomerase A (phosphoriboisomerase A); TIGRFAM: ribose 5-phosphate isomerase.
     
 0.927
Igag_1729
COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: sto:ST2268 transketolase; PFAM: Transketolase domain protein; SPTR: Q96YA0 273aa long hypothetical transketolase; PFAM: Transketolase, thiamine diphosphate binding domain.
  
 
 0.926
Igag_1229
COGs: COG1109 Phosphomannomutase; InterProIPR005841:IPR005844:IPR005843:IPR005845:IPR 016066; KEGG: smr:Smar_1286 phosphoglucomutase/phosphomannomutase alpha/beta/subunit; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; PRIAM: Phosphoglucosamine mutase; SPTR: A3DP17 Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha do [...]
    
 0.918
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 
 0.914
Igag_0412
COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002139:IPR011611:IPR013749:IPR002173; KEGG: dka:DKAM_0615 ATP-dependent 6-phosphofructokinase; PFAM: PfkB domain protein; Phosphomethylpyrimidine kinase type-1; SPTR: B8D4B0 ATP-dependent 6-phosphofructokinase; PFAM: pfkB family carbohydrate kinase.
  
 
 0.914
Igag_1635
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002139:IPR011611; KEGG: sto:ST2328 ribokinase; PFAM: PfkB domain protein; SPTR: Q96Y38 291aa long hypothetical ribokinase; PFAM: pfkB family carbohydrate kinase.
  
 
 0.914
Igag_1921
Orotidine 5'-phosphate decarboxylase; COGs: COG0269 3-hexulose-6-phosphate synthase and related protein; InterPro IPR001754; KEGG: siy:YG5714_2053 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; SPTR: C3N820 Orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: 3-hexulose-6-phosphate synthase.
    
  0.900
pdxS
Pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
   
 
  0.802
Your Current Organism:
Ignisphaera aggregans
NCBI taxonomy Id: 583356
Other names: I. aggregans DSM 17230, Ignisphaera aggregans DSM 17230, Ignisphaera aggregans str. DSM 17230, Ignisphaera aggregans strain DSM 17230
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