STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Igag_1782ParB domain protein nuclease; InterPro IPR003115; KEGG: hbu:Hbut_1584 transcriptional regulator; SMART: ParB domain protein nuclease; SPTR: A2BN43 Predicted transcriptional regulator; PFAM: ParB-like nuclease domain. (137 aa)    
Predicted Functional Partners:
Igag_1783
COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: pis:Pisl_1761 pyridoxal-5'-phosphate-dependent enzyme, beta subunit; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: A1RVD0 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme.
 
  
 0.985
Igag_0323
ParB domain protein nuclease; InterPro IPR003115; KEGG: sso:SSO0115 hypothetical protein; PFAM: ParB domain protein nuclease; SPTR: P95946 Putative uncharacterized protein; PFAM: ParB-like nuclease domain.
     
 
0.900
Igag_1394
HAD-superfamily hydrolase, subfamily IB (PSPase-like); COGs: COG0560 Phosphoserine phosphatase; InterPro IPR005834:IPR013200:IPR006383; KEGG: tsi:TSIB_1092 phosphoserine phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; Haloacid dehalogenase domain protein hydrolase type 3; SPTR: B5IST0 Phosphoserine phosphatase-like hydrolase, archaeal; TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like.
   
 
  0.900
Igag_1758
COGs: COG0460 Homoserine dehydrogenase; InterPro IPR001342:IPR005106:IPR019811; KEGG: mst:Msp_0487 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; PRIAM: Homoserine dehydrogenase; SPTR: Q2NH16 Putative homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase.
    
 0.818
Igag_1385
COGs: COG1171 Threonine dehydratase; InterPro IPR002912:IPR001926:IPR005789; KEGG: hbu:Hbut_0216 threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; SPTR: A2BJC7 Threonine dehydratase catabolic; TIGRFAM: threonine dehydratase; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form.
  
 
 0.817
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
     
  0.800
Igag_0303
Cobyrinic acid ac-diamide synthase; COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: sto:ST1320 hypothetical protein; PFAM: Cobyrinic acid ac-diamide synthase; SPTR: Q971P2 Putative uncharacterized protein ST1320; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
  
 
 0.752
Igag_1781
Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
  
    0.554
Igag_0914
CRISPR-associated autoregulator, DevR family; COGs: COG1857 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR002764:IPR010154; KEGG: tpe:Tpen_1356 CRISPR-associated autoregulator DevR family protein protein; PFAM: CRISPR-associated regulatory Csa2 family protein; SPTR: A1RZX3 CRISPR-associated autoregulator, DevR family; TIGRFAM: CRISPR-associated autoregulator DevR family; PFAM: CRISPR-associated negative autoregulator DevR/Csa2; TIGRFAM: CRISPR-associated autoregulator DevR family; CRISPR-associated regulatory protein, Csa2 family.
  
     0.497
Igag_1780
Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR008670:IPR015590; KEGG: dka:DKAM_1444 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde Dehydrogenase; acyl-CoA reductase; SPTR: B8D6N9 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde dehydrogenase family.
 
    0.470
Your Current Organism:
Ignisphaera aggregans
NCBI taxonomy Id: 583356
Other names: I. aggregans DSM 17230, Ignisphaera aggregans DSM 17230, Ignisphaera aggregans str. DSM 17230, Ignisphaera aggregans strain DSM 17230
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