| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADH59791.1 | ADH59792.1 | Tmath_0002 | Tmath_0003 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | TIGRFAM: S4 domain protein YaaA; PFAM: RNA-binding S4 domain protein; KEGG: tpd:Teth39_0003 RNA-binding S4 domain-containing protein; SMART: RNA-binding S4 domain protein. | 0.904 |
| ADH59791.1 | ADH59794.1 | Tmath_0002 | Tmath_0005 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: tpd:Teth39_0005 hypothetical protein. | 0.799 |
| ADH59791.1 | ADH59795.1 | Tmath_0002 | Tmath_0006 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Alpha-glucosidase; KEGG: tpd:Teth39_0006 alpha-glucosidase; PFAM: glycoside hydrolase family 31; Belongs to the glycosyl hydrolase 31 family. | 0.662 |
| ADH59791.1 | ADH60401.1 | Tmath_0002 | Tmath_0649 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: tex:Teth514_0537 ATP-dependent DNA helicase PcrA; TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase. | 0.949 |
| ADH59791.1 | dnaA | Tmath_0002 | Tmath_0001 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.994 |
| ADH59791.1 | gyrA | Tmath_0002 | Tmath_0010 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.621 |
| ADH59791.1 | gyrB | Tmath_0002 | Tmath_0009 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.803 |
| ADH59791.1 | polA | Tmath_0002 | Tmath_0850 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.994 |
| ADH59791.1 | recF | Tmath_0002 | Tmath_0004 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.955 |
| ADH59791.1 | recR | Tmath_0002 | Tmath_0102 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.484 |
| ADH59792.1 | ADH59791.1 | Tmath_0003 | Tmath_0002 | TIGRFAM: S4 domain protein YaaA; PFAM: RNA-binding S4 domain protein; KEGG: tpd:Teth39_0003 RNA-binding S4 domain-containing protein; SMART: RNA-binding S4 domain protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.904 |
| ADH59792.1 | ADH59794.1 | Tmath_0003 | Tmath_0005 | TIGRFAM: S4 domain protein YaaA; PFAM: RNA-binding S4 domain protein; KEGG: tpd:Teth39_0003 RNA-binding S4 domain-containing protein; SMART: RNA-binding S4 domain protein. | KEGG: tpd:Teth39_0005 hypothetical protein. | 0.818 |
| ADH59792.1 | ADH59795.1 | Tmath_0003 | Tmath_0006 | TIGRFAM: S4 domain protein YaaA; PFAM: RNA-binding S4 domain protein; KEGG: tpd:Teth39_0003 RNA-binding S4 domain-containing protein; SMART: RNA-binding S4 domain protein. | Alpha-glucosidase; KEGG: tpd:Teth39_0006 alpha-glucosidase; PFAM: glycoside hydrolase family 31; Belongs to the glycosyl hydrolase 31 family. | 0.717 |
| ADH59792.1 | dnaA | Tmath_0003 | Tmath_0001 | TIGRFAM: S4 domain protein YaaA; PFAM: RNA-binding S4 domain protein; KEGG: tpd:Teth39_0003 RNA-binding S4 domain-containing protein; SMART: RNA-binding S4 domain protein. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.657 |
| ADH59792.1 | recF | Tmath_0003 | Tmath_0004 | TIGRFAM: S4 domain protein YaaA; PFAM: RNA-binding S4 domain protein; KEGG: tpd:Teth39_0003 RNA-binding S4 domain-containing protein; SMART: RNA-binding S4 domain protein. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.948 |
| ADH59794.1 | ADH59791.1 | Tmath_0005 | Tmath_0002 | KEGG: tpd:Teth39_0005 hypothetical protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.799 |
| ADH59794.1 | ADH59792.1 | Tmath_0005 | Tmath_0003 | KEGG: tpd:Teth39_0005 hypothetical protein. | TIGRFAM: S4 domain protein YaaA; PFAM: RNA-binding S4 domain protein; KEGG: tpd:Teth39_0003 RNA-binding S4 domain-containing protein; SMART: RNA-binding S4 domain protein. | 0.818 |
| ADH59794.1 | ADH59795.1 | Tmath_0005 | Tmath_0006 | KEGG: tpd:Teth39_0005 hypothetical protein. | Alpha-glucosidase; KEGG: tpd:Teth39_0006 alpha-glucosidase; PFAM: glycoside hydrolase family 31; Belongs to the glycosyl hydrolase 31 family. | 0.752 |
| ADH59794.1 | dnaA | Tmath_0005 | Tmath_0001 | KEGG: tpd:Teth39_0005 hypothetical protein. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.425 |
| ADH59794.1 | recF | Tmath_0005 | Tmath_0004 | KEGG: tpd:Teth39_0005 hypothetical protein. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.889 |
