Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADH59890.1TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: tpd:Teth39_2195 metal dependent phosphohydrolase; SMART: metal-dependent phosphohydrolase HD region. (390 aa)    
Predicted Functional Partners:
ADH61652.1
Diguanylate cyclase with GAF sensor; SMART: GGDEF domain containing protein; GAF domain protein; TIGRFAM: diguanylate cyclase; KEGG: tex:Teth514_0822 diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein.
 
 0.881
ADH61709.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; GGDEF domain containing protein; PAS fold-3 domain protein; KEGG: tte:TTE1081 diguanylate cyclase/phosphodiesterase; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein.
 
  
 0.761
ADH59891.1
KEGG: tpd:Teth39_2194 hypothetical protein.
       0.627
crcB
CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
       0.610
crcB-2
CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
       0.610
ADH60258.1
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; thiamine pyrophosphate protein domain protein TPP-binding; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain; Pyruvate/ketoisovalerate oxidoreductase; KEGG: tpd:Teth39_1842 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
   0.540
ADH61705.1
KEGG: tpd:Teth39_0289 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
   0.533
ADH59884.1
TIGRFAM: PAS sensor protein; metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; PAS fold domain protein; histidine kinase HAMP region domain protein; KEGG: tex:Teth514_0032 putative PAS/PAC sensor protein; SMART: metal-dependent phosphohydrolase HD region; PAS domain containing protein; PAC repeat-containing protein; histidine kinase HAMP region domain protein; GAF domain protein.
 
   
0.505
ADH59892.1
KEGG: tpd:Teth39_2193 sigmaK-factor processing regulatory BofA; TIGRFAM: pro-sigmaK processing inhibitor BofA; PFAM: sigmaK-factor processing regulatory BofA.
       0.493
pheT
TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: tex:Teth514_2049 phenylalanyl-tRNA synthetase subunit beta.
  
 
 0.484
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.