Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH59918.1Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: tpd:Teth39_2159 LysR family transcriptional regulator. (297 aa)    
Predicted Functional Partners:
ADH59917.1
PFAM: SirA family protein; KEGG: tpd:Teth39_2160 hypothetical protein; Belongs to the sulfur carrier protein TusA family.
 
   
 0.870
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.787
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.714
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.712
ADH59919.1
PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: tex:Teth514_0045 protein of unknown function DUF395, YeeE/YedE.
 
     0.679
ADH60725.1
KEGG: tex:Teth514_1376 CRP/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: regulatory protein Crp; cyclic nucleotide-binding.
  
 
 0.626
ADH59920.1
PFAM: SirA family protein; KEGG: tpd:Teth39_2157 SirA family protein; Belongs to the sulfur carrier protein TusA family.
 
   
 0.613
ADH59921.1
PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: tpd:Teth39_2156 protein of unknown function DUF395, YeeE/YedE.
 
     0.588
ADH59922.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tpd:Teth39_2155 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
     
 0.579
ADH61921.1
KEGG: tpd:Teth39_2267 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp.
   
 
 0.561
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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