Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH59930.1TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: tpd:Teth39_2147 DNA polymerase III, delta prime subunit. (324 aa)    
Predicted Functional Partners:
ADH60656.1
KEGG: tex:Teth514_2091 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta.
 
 
 0.997
ADH59791.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.995
ADH61329.1
DNA polymerase III, alpha subunit; SMART: phosphoesterase PHP domain protein; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: tex:Teth514_1192 DNA polymerase III DnaE; PFAM: DNA polymerase III alpha subunit; nucleic acid binding OB-fold tRNA/helicase-type; PHP domain protein.
 
 0.992
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
  
 
0.982
polC
DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.915
ADH60549.1
PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: tex:Teth514_2188 single-stranded DNA-binding protein.
  
 
 0.866
ADH59931.1
PFAM: PSP1 domain protein; KEGG: tpd:Teth39_2146 PSP1 domain-containing protein.
  
   0.865
ADH59928.1
PFAM: protein of unknown function DUF970; KEGG: tpd:Teth39_2149 hypothetical protein.
  
    0.856
ADH59929.1
PFAM: protein of unknown function DUF327; KEGG: tpd:Teth39_2148 hypothetical protein.
       0.845
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
  
 0.836
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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