Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH59931.1PFAM: PSP1 domain protein; KEGG: tpd:Teth39_2146 PSP1 domain-containing protein. (292 aa)    
Predicted Functional Partners:
rny
Metal dependent phosphohydrolase; Endoribonuclease that initiates mRNA decay.
 
  
 0.889
ADH59929.1
PFAM: protein of unknown function DUF327; KEGG: tpd:Teth39_2148 hypothetical protein.
  
  
 0.872
ADH59930.1
TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: tpd:Teth39_2147 DNA polymerase III, delta prime subunit.
  
   0.865
ADH59928.1
PFAM: protein of unknown function DUF970; KEGG: tpd:Teth39_2149 hypothetical protein.
  
    0.856
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
    0.826
ADH59926.1
Arginine decarboxylase; KEGG: tpd:Teth39_2151 Orn/Lys/Arg decarboxylase, major region; PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein.
  
    0.818
ADH59925.1
PFAM: Sigma-G inhibitor, Gin; KEGG: tpd:Teth39_2152 hypothetical protein.
       0.599
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.414
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
       0.406
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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