Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH59933.1PFAM: methyltransferase small; KEGG: tpd:Teth39_2144 methyltransferase small. (248 aa)    
Predicted Functional Partners:
rsmI
Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
  
  
 0.927
tmcAL
Protein of unknown function DUF795; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
 
     0.733
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
    0.545
arcA
KEGG: tpd:Teth39_2145 arginine deiminase; PFAM: amidinotransferase.
       0.530
ADH59935.1
KEGG: tpd:Teth39_2142 cation diffusion facilitator family transporter; TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
       0.502
ADH61506.1
TIGRFAM: RNA methylase, NOL1/NOP2/sun family; KEGG: tex:Teth514_0979 NOL1/NOP2/sun family RNA methylase; PFAM: Fmu (Sun) domain protein.
 
     0.494
ADH61924.1
Phosphoesterase RecJ domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
  
     0.482
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
     0.474
ADH61027.1
KEGG: tex:Teth514_1719 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
  
     0.463
ADH59929.1
PFAM: protein of unknown function DUF327; KEGG: tpd:Teth39_2148 hypothetical protein.
 
    0.420
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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