Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH60042.1KEGG: tex:Teth514_0161 periplasmic binding protein/LacI transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI. (336 aa)    
Predicted Functional Partners:
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 0.849
rbsD
RbsD or FucU transport; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
  
  
 0.766
ADH60046.1
PFAM: inner-membrane translocator; KEGG: tpd:Teth39_2039 monosaccharide-transporting ATPase; Belongs to the binding-protein-dependent transport system permease family.
  
  
 0.734
rbsA
ABC transporter related protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
  
  
 0.717
ADH61331.1
KEGG: tpd:Teth39_0679 phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr.
   
 
 0.626
ADH60047.1
PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: tpd:Teth39_2038 monosaccharide-transporting ATPase.
 
  
0.588
ADH60041.1
PFAM: protein of unknown function DUF820; KEGG: tpd:Teth39_2031 hypothetical protein.
       0.470
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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