Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rbsDRbsD or FucU transport; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (130 aa)    
Predicted Functional Partners:
ADH60046.1
PFAM: inner-membrane translocator; KEGG: tpd:Teth39_2039 monosaccharide-transporting ATPase; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.996
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
  
 0.995
ADH60047.1
PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: tpd:Teth39_2038 monosaccharide-transporting ATPase.
 
  
 0.984
rbsA
ABC transporter related protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
 
  
 0.971
ADH60103.1
PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: tex:Teth514_0222 periplasmic binding protein/LacI transcriptional regulator.
 
  
 0.891
xylG
ABC transporter related protein; Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family.
  
  
 0.870
ADH60042.1
KEGG: tex:Teth514_0161 periplasmic binding protein/LacI transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI.
  
  
 0.766
ADH60140.1
Transcriptional regulator, MarR family; PFAM: PfkB domain protein; regulatory protein MarR; KEGG: tpd:Teth39_1953 ribokinase-like domain-containing protein.
  
  
 0.465
ADH60041.1
PFAM: protein of unknown function DUF820; KEGG: tpd:Teth39_2031 hypothetical protein.
       0.453
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
      
 0.412
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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