Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ADH60080.1KEGG: tex:Teth514_0198 RND family efflux transporter MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: biotin/lipoyl attachment domain-containing protein; secretion protein HlyD family protein. (588 aa)    
Predicted Functional Partners:
ADH60082.1
PFAM: protein of unknown function DUF214; KEGG: tpd:Teth39_2013 hypothetical protein.
 
 0.994
ADH60801.1
PFAM: protein of unknown function DUF214; KEGG: tpd:Teth39_1031 hypothetical protein.
 
 0.981
macB
ABC transporter related protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 0.978
ADH60802.1
KEGG: tpd:Teth39_1032 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 0.922
ADH60716.1
KEGG: tex:Teth514_2375 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 0.844
ADH60803.1
TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: tpd:Teth39_1033 RND family efflux transporter MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
 
0.821
ADH60251.1
KEGG: cbf:CLI_0667 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 0.670
ADH60715.1
PFAM: protein of unknown function DUF214; KEGG: tex:Teth514_2376 hypothetical protein.
  
 0.589
ADH60079.1
KEGG: tpd:Teth39_2016 MATE efflux family protein; TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE.
     
 0.557
dinB
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
       0.535
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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