STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (311 aa)    
Predicted Functional Partners:
ADH60258.1
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; thiamine pyrophosphate protein domain protein TPP-binding; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain; Pyruvate/ketoisovalerate oxidoreductase; KEGG: tpd:Teth39_1842 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
 
 0.993
ADH61705.1
KEGG: tpd:Teth39_0289 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
 
 0.993
ADH61326.1
Pyruvate kinase; KEGG: tex:Teth514_1195 pyruvate kinase., pyruvate, water dikinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family.
  
 0.989
ADH61649.1
PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: tex:Teth514_0830 malate dehydrogenase.
  
 0.955
ADH61564.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: tex:Teth514_0942 2-ketoisovalerate ferredoxin reductase.
  
 
 0.951
ADH60929.1
PFAM: aminotransferase class I and II; KEGG: tpd:Teth39_1184 aspartate aminotransferase.
  
 0.940
ADH60705.1
TIGRFAM: pyruvate, phosphate dikinase; KEGG: tpd:Teth39_1358 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; Belongs to the PEP-utilizing enzyme family.
  
 
 0.935
ADH61563.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: tpd:Teth39_0466 thiamine pyrophosphate binding domain-containing protein.
  
 
 0.928
ADH60903.1
PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; KEGG: tpd:Teth39_1145 oxaloacetate decarboxylase.
    
 0.926
pgi
KEGG: tpd:Teth39_0694 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); Belongs to the GPI family.
  
 
 0.925
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.