Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ADH60130.1PFAM: regulatory protein TetR; KEGG: tpd:Teth39_1964 TetR family transcriptional regulator. (194 aa)    
Predicted Functional Partners:
ADH60131.1
PFAM: Protein of unknown function DUF2229, CoA enzyme activase; KEGG: tpd:Teth39_1963 hypothetical protein.
       0.627
ADH60132.1
KEGG: tex:Teth514_0250 hypothetical protein.
       0.627
ADH60133.1
KEGG: tpd:Teth39_1960 putative CoA-substrate-specific enzyme activase; TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type.
       0.625
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
    0.537
ADH61652.1
Diguanylate cyclase with GAF sensor; SMART: GGDEF domain containing protein; GAF domain protein; TIGRFAM: diguanylate cyclase; KEGG: tex:Teth514_0822 diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein.
  
 
 0.534
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.515
ADH60129.1
KEGG: tex:Teth514_0244 aminopeptidase-like protein.
 
     0.487
ADH60242.1
PFAM: ABC-2 type transporter; KEGG: tro:trd_A0466 putative integral membrane protein.
 
     0.416
ADH61709.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; GGDEF domain containing protein; PAS fold-3 domain protein; KEGG: tte:TTE1081 diguanylate cyclase/phosphodiesterase; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein.
  
   
 0.415
ADH60228.1
PFAM: major facilitator superfamily MFS_1; KEGG: tte:TTE0395 major facilitator superfamily permease.
 
  
 0.414
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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