Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADH60237.1Hypothetical protein; KEGG: cbh:CLC_0562 streptolysin associated protein SagC. (209 aa)    
Predicted Functional Partners:
ADH60307.1
PFAM: thiamineS protein; KEGG: tte:TTE2469 hypothetical protein.
  
 0.941
ADH60235.1
KEGG: bdu:BDU_514 p-512 protein.
       0.780
ADH60236.1
KEGG: ptm:GSPATT00017601001 hypothetical protein.
       0.780
ADH60243.1
PFAM: protein of unknown function DUF181; KEGG: sai:Saci_0526 hypothetical protein.
     
 0.717
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.716
ADH60238.1
Hypothetical protein; KEGG: pfd:PFDG_01032 conserved hypothetical protein.
       0.715
ADH60420.1
KEGG: tex:Teth514_0565 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.
  
  
 0.715
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.711
ADH60239.1
KEGG: svi:Svir_09420 nitroreductase; TIGRFAM: SagB-type dehydrogenase domain; PFAM: nitroreductase.
       0.667
ADH60242.1
PFAM: ABC-2 type transporter; KEGG: tro:trd_A0466 putative integral membrane protein.
       0.666
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
Server load: low (28%) [HD]