Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADH60318.1KEGG: tex:Teth514_0453 hypothetical protein. (185 aa)    
Predicted Functional Partners:
ADH60315.1
PFAM: FlgN family protein; KEGG: tpd:Teth39_1785 hypothetical protein.
 
  
 0.958
ADH60317.1
KEGG: tpd:Teth39_1783 flagellar hook-associated protein FlgL; TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein.
 
  
 0.915
ADH60313.1
KEGG: tpd:Teth39_1787 hypothetical protein.
 
  
 0.914
flgK
KEGG: tpd:Teth39_1784 flagellar hook-associated protein FlgK; TIGRFAM: flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein.
 
  
 0.890
fliW
Protein of unknown function DUF180; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
  
 0.872
ADH60314.1
PFAM: Anti-sigma-28 factor FlgM family protein; KEGG: tpd:Teth39_1786 hypothetical protein.
  
  
 0.842
csrA
Carbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
 
    0.770
ADH60555.1
KEGG: tex:Teth514_2182 hypothetical protein.
  
     0.624
ADH59929.1
PFAM: protein of unknown function DUF327; KEGG: tpd:Teth39_2148 hypothetical protein.
 
     0.615
ADH60789.1
KEGG: tpd:Teth39_1019 hypothetical protein.
  
     0.612
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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