Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADH60338.1PFAM: 3H domain protein; Helix-turn-helix type 11 domain protein; KEGG: tpd:Teth39_1758 3H domain-containing protein. (170 aa)    
Predicted Functional Partners:
ADH60336.1
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: tex:Teth514_0473 metal dependent phosphohydrolase; SMART: metal-dependent phosphohydrolase HD region.
       0.780
ADH60337.1
KEGG: tex:Teth514_0474 hypothetical protein.
       0.780
ADH60339.1
KEGG: tex:Teth514_0476 hypothetical protein.
 
   
 0.706
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
  
 0.540
ADH60335.1
KEGG: tpd:Teth39_1761 hypothetical protein.
 
     0.505
ADH60589.1
PFAM: Quinolinate phosphoribosyl transferase; KEGG: tpd:Teth39_1471 nicotinate phosphoribosyltransferase; Belongs to the NAPRTase family.
 
   
 0.465
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
   
 0.443
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
Server load: low (16%) [HD]