Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH60355.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: tpd:Teth39_1741 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (316 aa)    
Predicted Functional Partners:
ADH60607.1
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
 
  
   0.614
ADH61846.1
PFAM: aminotransferase class V; KEGG: tpd:Teth39_0144 alanine--glyoxylate transaminase.
  
 
 0.571
ADH61853.1
SMART: beta-lactamase domain protein; KEGG: tpd:Teth39_0137 beta-lactamase domain-containing protein.
   
    0.542
tsaD
Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
       0.470
ADH60351.1
PFAM: protein of unknown function UPF0079; KEGG: tpd:Teth39_1745 hypothetical protein.
  
    0.465
ADH60353.1
Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.
  
    0.465
ADH60352.1
PFAM: peptidase M22 glycoprotease; KEGG: tex:Teth514_0489 peptidase M22, glycoprotease.
       0.450
ADH61284.1
KEGG: tpd:Teth39_0715 phosphoribulokinase/uridine kinase; PFAM: phosphoribulokinase/uridine kinase; SMART: AAA ATPase.
   
  0.412
ADH61299.1
PFAM: homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; dihydropteroate synthase DHPS; KEGG: tpd:Teth39_0697 homocysteine S-methyltransferase.
   
  
 0.405
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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