| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADH60409.1 | ADH60410.1 | Tmath_0657 | Tmath_0658 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Phosphodiesterase, MJ0936 family; KEGG: tpd:Teth39_1681 phosphodiesterase; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase. | 0.938 |
| ADH60409.1 | rph | Tmath_0657 | Tmath_0656 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.992 |
| ADH60410.1 | ADH60409.1 | Tmath_0658 | Tmath_0657 | Phosphodiesterase, MJ0936 family; KEGG: tpd:Teth39_1681 phosphodiesterase; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.938 |
| ADH60410.1 | rph | Tmath_0658 | Tmath_0656 | Phosphodiesterase, MJ0936 family; KEGG: tpd:Teth39_1681 phosphodiesterase; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.861 |
| ADH60800.1 | rnr | Tmath_1080 | Tmath_0974 | SMART: beta-lactamase domain protein; KEGG: tpd:Teth39_1030 beta-lactamase domain-containing protein. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.756 |
| ADH60800.1 | rph | Tmath_1080 | Tmath_0656 | SMART: beta-lactamase domain protein; KEGG: tpd:Teth39_1030 beta-lactamase domain-containing protein. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.781 |
| ADH61214.1 | rph | Tmath_1503 | Tmath_0656 | Regulatory protein DeoR; KEGG: chy:CHY_0837 DNA repair protein RadA; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.883 |
| ADH61246.1 | pnp | Tmath_1536 | Tmath_1232 | KEGG: tpd:Teth39_0757 cold-shock DNA-binding domain-containing protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.830 |
| ADH61246.1 | rnr | Tmath_1536 | Tmath_0974 | KEGG: tpd:Teth39_0757 cold-shock DNA-binding domain-containing protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.852 |
| ADH61246.1 | rph | Tmath_1536 | Tmath_0656 | KEGG: tpd:Teth39_0757 cold-shock DNA-binding domain-containing protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.806 |
| ADH61246.1 | rpsD | Tmath_1536 | Tmath_1906 | KEGG: tpd:Teth39_0757 cold-shock DNA-binding domain-containing protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein. | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.523 |
| ADH61246.1 | rpsK | Tmath_1536 | Tmath_1907 | KEGG: tpd:Teth39_0757 cold-shock DNA-binding domain-containing protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.734 |
| dnaG | rph | Tmath_1555 | Tmath_0656 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.844 |
| dnaG | rpsK | Tmath_1555 | Tmath_1907 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.403 |
| pnp | ADH61246.1 | Tmath_1232 | Tmath_1536 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | KEGG: tpd:Teth39_0757 cold-shock DNA-binding domain-containing protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein. | 0.830 |
| pnp | rnr | Tmath_1232 | Tmath_0974 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.887 |
| pnp | rph | Tmath_1232 | Tmath_0656 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.835 |
| pnp | rpsD | Tmath_1232 | Tmath_1906 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.868 |
| pnp | rpsK | Tmath_1232 | Tmath_1907 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.797 |
| rnr | ADH60800.1 | Tmath_0974 | Tmath_1080 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | SMART: beta-lactamase domain protein; KEGG: tpd:Teth39_1030 beta-lactamase domain-containing protein. | 0.756 |
