Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH60430.1PFAM: Extracellular ligand-binding receptor; KEGG: chy:CHY_2238 high affinity branched-chain amino acid ABC transporter, amino acid-binding protein. (389 aa)    
Predicted Functional Partners:
ADH60427.1
ABC transporter related protein; KEGG: chy:CHY_2229 high affinity branched-chain amino acid ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 
 0.999
ADH60428.1
PFAM: inner-membrane translocator; KEGG: chy:CHY_2230 high affinity branched-chain amino acid ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.999
ADH60429.1
PFAM: inner-membrane translocator; KEGG: chy:CHY_2231 high affinity branched-chain amino acid ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.999
ADH60426.1
KEGG: tex:Teth514_0572 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 
 0.998
ADH60560.1
KEGG: tpd:Teth39_1495 response regulator receiver/ANTAR domain-containing protein; PFAM: ANTAR domain protein; response regulator receiver; SMART: response regulator receiver.
  
 
 0.817
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
    0.501
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
    0.413
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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