Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH60544.1Peptidase S8 and S53 subtilisin kexin sedolisin; Serine protease with a broad substrate specificity. (576 aa)    
Predicted Functional Partners:
ADH60482.1
PFAM: conserved hypothetical protein; KEGG: tpd:Teth39_1609 hypothetical protein.
 
 0.747
ADH60542.1
PFAM: extracellular solute-binding protein family 1; KEGG: tpd:Teth39_1513 extracellular solute-binding protein.
  
     0.546
ADH61776.1
KEGG: tpd:Teth39_0213 phosphoesterase, PA-phosphatase related; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related.
 
 
 0.466
ADH60606.1
KEGG: tpd:Teth39_1455 hypothetical protein.
  
     0.442
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
  0.437
ADH60548.1
KEGG: tpd:Teth39_1507 Mur ligase middle domain-containing protein.
  
     0.420
ADH61442.1
PFAM: AMP-dependent synthetase and ligase; KEGG: tpd:Teth39_0579 AMP-dependent synthetase and ligase.
  
 
 0.413
ADH61576.1
KEGG: tpd:Teth39_0446 peptidoglycan binding domain-containing protein; PFAM: Peptidoglycan-binding domain 1 protein; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM.
  
  
 0.413
ADH61691.1
PFAM: sodium pump decarboxylase gamma subunit; KEGG: tpd:Teth39_0306 hypothetical protein.
  
     0.413
ADH59946.1
PFAM: S-layer domain protein; KEGG: tte:TTE0116 S-layer-like domain-containing protein.
 
    0.412
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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