Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADH60550.1PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; KEGG: tex:Teth514_2187 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. (175 aa)    
Predicted Functional Partners:
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.991
ADH60191.1
KEGG: tex:Teth514_0305 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; PFAM: cobalbumin biosynthesis protein.
 
 
 0.978
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.976
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.976
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 
 0.959
ADH60205.1
KEGG: tpd:Teth39_1890 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4.
     
 0.720
ADH61299.1
PFAM: homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; dihydropteroate synthase DHPS; KEGG: tpd:Teth39_0697 homocysteine S-methyltransferase.
     
 0.704
ADH60549.1
PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: tex:Teth514_2188 single-stranded DNA-binding protein.
       0.681
ADH60194.1
KEGG: tex:Teth514_0308 precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase CbiC/CobH.
 
   
 0.589
ADH60197.1
TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; KEGG: tex:Teth514_0311 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit.
 
   
 0.566
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.