Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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ADH60561.1Isoaspartyl dipeptidase; Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation. Belongs to the peptidase M38 family. (389 aa)    
Predicted Functional Partners:
pyrB
TIGRFAM: aspartate carbamoyltransferase; KEGG: tpd:Teth39_1345 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 
 0.965
pyrD
Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate.
  
 
 0.841
carA
KEGG: tpd:Teth39_0227 carbamoyl phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family.
  
  
 0.835
pyrF
TIGRFAM: orotidine 5'-phosphate decarboxylase; KEGG: tpd:Teth39_1343 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
  
 0.833
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.830
carB
KEGG: tex:Teth514_0662 carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein.
  
 
 0.773
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
  
 
 0.701
ADH61916.1
KEGG: tpd:Teth39_2266 uracil-xanthine permease; TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease.
  
  
 0.612
ADH60562.1
KEGG: tex:Teth514_2175 GntR family transcriptional regulator; PFAM: aminotransferase class I and II; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH.
  
   0.592
ADH60175.1
KEGG: tpd:Teth39_1916 anaerobic sulfite reductase subunit B; TIGRFAM: sulfite reductase, subunit B; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; Oxidoreductase FAD-binding domain protein.
  
  
 0.494
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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