Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH60624.1PFAM: protein of unknown function DUF988; KEGG: tpd:Teth39_1437 hypothetical protein. (160 aa)    
Predicted Functional Partners:
queF
7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
 
     0.817
ADH60821.1
PFAM: protein of unknown function DUF988; KEGG: tex:Teth514_1496 hypothetical protein.
  
     0.713
ADH60711.1
KEGG: tpd:Teth39_0937 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
  
     0.613
ADH61671.1
Transcriptional regulator, XRE family; KEGG: tte:TTE2364 hypothetical protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
  
     0.534
ADH60626.1
PFAM: protein of unknown function UPF0236; KEGG: tte:TTE2708 hypothetical protein.
 
     0.521
queA
S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
  
     0.497
ADH60721.1
PFAM: protein of unknown function DUF990; KEGG: tte:TTE2236 hypothetical protein.
  
     0.479
ADH60625.1
PFAM: protein of unknown function UPF0236; KEGG: tte:TTE2708 hypothetical protein.
       0.446
tgt
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]
  
     0.417
ADH61837.1
KEGG: tte:TTE2606 hypothetical protein; PFAM: copper amine oxidase domain protein; SH3 type 3 domain protein; SMART: SH3 domain protein.
  
     0.409
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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