Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH60634.1TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: tpd:Teth39_1428 metal dependent phosphohydrolase; SMART: metal-dependent phosphohydrolase HD region. (194 aa)    
Predicted Functional Partners:
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
    0.998
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
  
 0.971
ADH60635.1
KEGG: tte:TTE0920 transcriptional regulator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator.
 
    0.856
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
    0.612
polC
DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
     0.567
ADH60827.1
KEGG: tpd:Teth39_1065 HAD family phosphatase; TIGRFAM: HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Haloacid dehalogenase domain protein hydrolase.
 
  
 0.562
ADH60627.1
KEGG: tex:Teth514_2118 hypothetical protein.
   
    0.542
ADH60637.1
PFAM: YheO domain protein; KEGG: tpd:Teth39_1426 YheO domain-containing protein.
       0.501
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
    0.474
cinA
Competence/damage-inducible protein CinA; KEGG: tpd:Teth39_1192 competence damage-inducible protein A; TIGRFAM: competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; Belongs to the CinA family.
 
   
 0.469
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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