Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pcpPyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family. (202 aa)    
Predicted Functional Partners:
ADH60723.1
PFAM: protein of unknown function DUF979; KEGG: tex:Teth514_1373 hypothetical protein.
 
    0.946
ADH60722.1
PFAM: protein of unknown function DUF969; KEGG: tte:TTE1610 hypothetical protein.
 
     0.943
ADH60313.1
KEGG: tpd:Teth39_1787 hypothetical protein.
   
   0.815
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
   0.812
ADH60927.1
TIGRFAM: stage V sporulation protein K; PFAM: AAA ATPase central domain protein; KEGG: tex:Teth514_1619 ATPase central domain-containing protein; SMART: AAA ATPase.
    
   0.810
ADH61481.1
KEGG: tex:Teth514_1019 MIP family channel protein; TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
   0.807
ADH61295.1
KEGG: tpd:Teth39_0701 hypothetical protein.
    
   0.801
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
   0.796
ADH60725.1
KEGG: tex:Teth514_1376 CRP/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: regulatory protein Crp; cyclic nucleotide-binding.
 
 
   0.696
ADH59802.1
PFAM: protein of unknown function UPF0236; KEGG: tte:TTE2708 hypothetical protein.
    
   0.522
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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