Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pheAKEGG: tex:Teth514_1424 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein. (274 aa)    
Predicted Functional Partners:
ADH60751.1
PFAM: Prephenate dehydrogenase; KEGG: tpd:Teth39_0985 prephenate dehydrogenase.
 
 0.993
ADH60929.1
PFAM: aminotransferase class I and II; KEGG: tpd:Teth39_1184 aspartate aminotransferase.
 
 
 0.980
ADH60750.1
TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: tpd:Teth39_0984 3-deoxy-7-phosphoheptulonate synthase; PFAM: DAHP synthetase I/KDSA.
 
  
 0.979
ADH61851.1
KEGG: tpd:Teth39_0139 hypothetical protein; Belongs to the UPF0735 family.
  
 
 0.959
hisC
KEGG: tpd:Teth39_0517 histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
 
 0.933
ADH60913.1
Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
    
 0.918
ADH61128.1
TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: tpd:Teth39_0895 3-deoxy-7-phosphoheptulonate synthase; PFAM: DAHP synthetase I/KDSA.
 
  
 0.906
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
  
 0.868
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
  
 0.828
ADH60066.1
PFAM: aminotransferase class I and II; KEGG: tpd:Teth39_2027 aminotransferase, class I and II.
 
  
 0.700
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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