Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rnjRNA-metabolising metallo-beta-lactamase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (554 aa)    
Predicted Functional Partners:
ADH60820.1
PFAM: protein of unknown function DUF964; KEGG: tpd:Teth39_1058 hypothetical protein; Belongs to the UPF0342 family.
       0.796
ADH60821.1
PFAM: protein of unknown function DUF988; KEGG: tex:Teth514_1496 hypothetical protein.
       0.766
rny
Metal dependent phosphohydrolase; Endoribonuclease that initiates mRNA decay.
  
 
 0.671
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
  
    0.662
ADH60823.1
PFAM: O-methyltransferase family 3; KEGG: tpd:Teth39_1061 O-methyltransferase family protein.
       0.636
ADH60818.1
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: tpd:Teth39_1056 ferric uptake regulator family protein; Belongs to the Fur family.
       0.597
ADH60863.1
PFAM: Polyprenyl synthetase; KEGG: tex:Teth514_1538 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
    0.592
ADH61743.1
PFAM: Polyprenyl synthetase; KEGG: tex:Teth514_0672 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
    0.592
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
    0.581
ybeY
Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
 
  
 0.564
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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