Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH60826.1RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (231 aa)    
Predicted Functional Partners:
ADH60871.1
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.829
ADH59982.1
TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: tex:Teth514_0108 regulatory protein, DeoR.
  
   
 0.775
ADH60870.1
SMART: PDZ/DHR/GLGF domain protein; TIGRFAM: stage IV sporulation protein B; KEGG: tex:Teth514_1545 peptidase S55, SpoIVB; PFAM: peptidase S55 SpoIVB.
  
   
 0.773
ADH61156.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
     0.771
ADH60887.1
KEGG: tpd:Teth39_1124 SpoVA protein; TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein.
  
     0.769
ADH60888.1
KEGG: tpd:Teth39_1125 stage V sporulation protein AD; TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein.
  
     0.769
ADH60889.1
KEGG: tpd:Teth39_1126 SpoVA protein; TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein.
  
     0.769
ADH60853.1
KEGG: tpd:Teth39_1091 hypothetical protein; TIGRFAM: stage III sporulation protein AD; PFAM: Sporulation stage III protein AD.
 
     0.767
gpr
Spore protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
     0.766
ADH60856.1
TIGRFAM: stage III sporulation protein AG; KEGG: tpd:Teth39_1094 hypothetical protein.
 
     0.766
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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