Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH60883.1KEGG: tpd:Teth39_1120 anti-sigma-factor antagonist; TIGRFAM: anti-sigma F factor antagonist; anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS. (111 aa)    
Predicted Functional Partners:
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.997
ADH60885.1
RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; KEGG: tex:Teth514_1559 FliA/WhiG family RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-F factor; RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; sigma-70 region 3 domain protein.
 
  
 0.967
ADH60888.1
KEGG: tpd:Teth39_1125 stage V sporulation protein AD; TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein.
 
   
 0.837
ADH60887.1
KEGG: tpd:Teth39_1124 SpoVA protein; TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein.
 
   
 0.835
ADH60889.1
KEGG: tpd:Teth39_1126 SpoVA protein; TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein.
 
     0.820
ADH60597.1
PFAM: ATP-binding region ATPase domain protein; KEGG: tex:Teth514_2146 putative anti-sigma regulatory factor, serine/threonine protein kinase.
  
 
 0.805
ADH61699.1
SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: tex:Teth514_0790 phosphoprotein phosphatase; PFAM: Stage II sporulation E family protein.
  
  
 0.776
ADH61156.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.770
ADH61798.1
KEGG: tex:Teth514_0606 hypothetical protein; TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R.
  
   
 0.728
ADH59982.1
TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: tex:Teth514_0108 regulatory protein, DeoR.
  
   
 0.721
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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