Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADH61033.1PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tex:Teth514_0560 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein. (149 aa)    
Predicted Functional Partners:
ADH61032.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tpd:Teth39_1658 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 
 
 0.993
ADH60605.1
TIGRFAM: hydrogenase, Fe-only; PFAM: hydrogenase large subunit domain protein; iron hydrogenase small subunit; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; KEGG: tpd:Teth39_1456 hydrogenase, Fe-only; SMART: iron hydrogenase small subunit.
  
 
 0.964
ADH61035.1
PFAM: glutamine amidotransferase class-II; KEGG: tpd:Teth39_1661 glutamine amidotransferase, class-II.
 
    0.945
ADH61031.1
PFAM: glutamate synthase alpha subunit domain protein; KEGG: tpd:Teth39_1657 glutamate synthase alpha subunit.
 
     0.933
ADH61034.1
KEGG: tex:Teth514_0559 glutamate synthase (NADPH); PFAM: ferredoxin-dependent glutamate synthase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Belongs to the glutamate synthase family.
 
   
 0.933
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
 
 0.880
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
    0.791
ADH61313.1
PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: tte:TTE0125 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductase; Belongs to the complex I 20 kDa subunit family.
    
 0.785
ADH61314.1
PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: tte:TTE0124 NADH:ubiquinone oxidoreductase subunit 1 (chain H).
    
  0.773
ADH60258.1
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; thiamine pyrophosphate protein domain protein TPP-binding; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain; Pyruvate/ketoisovalerate oxidoreductase; KEGG: tpd:Teth39_1842 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
     
 0.767
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.