Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ADH61086.1KEGG: tpd:Teth39_1329 hypothetical protein. (175 aa)    
Predicted Functional Partners:
ADH61085.1
PFAM: major facilitator superfamily MFS_1; KEGG: tpd:Teth39_1328 major facilitator transporter.
 
     0.829
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
       0.535
ADH61087.1
PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: tpd:Teth39_1330 fibronectin-binding A domain-containing protein.
       0.502
ADH61885.1
PFAM: YycH family protein; KEGG: tte:TTE2686 hypothetical protein.
  
     0.445
ADH61083.1
PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: tex:Teth514_1763 hypothetical protein.
       0.433
ADH61082.1
PFAM: protein of unknown function DUF370; KEGG: tpd:Teth39_1325 hypothetical protein; Belongs to the RemA family.
       0.429
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
       0.428
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
       0.425
ADH60228.1
PFAM: major facilitator superfamily MFS_1; KEGG: tte:TTE0395 major facilitator superfamily permease.
 
     0.420
ADH61079.1
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
       0.420
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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