Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH61156.1Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. (492 aa)    
Predicted Functional Partners:
ADH60853.1
KEGG: tpd:Teth39_1091 hypothetical protein; TIGRFAM: stage III sporulation protein AD; PFAM: Sporulation stage III protein AD.
  
  
 0.919
ADH59980.1
KEGG: tpd:Teth39_2097 SpoIID/LytB domain-containing protein; TIGRFAM: stage II sporulation protein D; SpoIID/LytB domain protein; PFAM: Stage II sporulation D domain protein.
  
  
 0.887
ADH59982.1
TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: tex:Teth514_0108 regulatory protein, DeoR.
  
  
 0.878
ADH60850.1
KEGG: tex:Teth514_1525 AAA ATPase; TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase.
  
  
 0.859
ADH60871.1
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.853
ADH60852.1
KEGG: tpd:Teth39_1090 stage III sporulation AC family protein; TIGRFAM: stage III sporulation protein AC; PFAM: Stage III sporulation AC family protein.
  
  
 0.850
ADH61798.1
KEGG: tex:Teth514_0606 hypothetical protein; TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R.
  
   
 0.847
ADH60856.1
TIGRFAM: stage III sporulation protein AG; KEGG: tpd:Teth39_1094 hypothetical protein.
  
  
 0.845
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.837
ADH60857.1
KEGG: tex:Teth514_1532 hypothetical protein.
  
  
 0.836
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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