Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADH61200.1PFAM: aminotransferase class V; KEGG: tex:Teth514_2025 aminotransferase, class V. (383 aa)    
Predicted Functional Partners:
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 0.998
ADH60179.1
KEGG: tpd:Teth39_1910 NifU family SUF system FeS assembly protein; TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein.
 
 0.948
ADH61869.1
KEGG: tpd:Teth39_0120 NifU family SUF system FeS assembly protein; TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein.
 
 0.948
iscS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
  
 
0.904
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 0.896
ADH59917.1
PFAM: SirA family protein; KEGG: tpd:Teth39_2160 hypothetical protein; Belongs to the sulfur carrier protein TusA family.
   
 0.815
ADH59920.1
PFAM: SirA family protein; KEGG: tpd:Teth39_2157 SirA family protein; Belongs to the sulfur carrier protein TusA family.
   
 0.815
ADH60308.1
PFAM: PP-loop domain protein; KEGG: csc:Csac_0104 PP-loop domain-containing protein; Belongs to the TtcA family.
    
 0.774
ADH61093.1
PFAM: PP-loop domain protein; KEGG: tex:Teth514_1810 PP-loop domain-containing protein; Belongs to the TtcA family.
    
 0.773
ADH61250.1
PFAM: nitrogen-fixing NifU domain protein; KEGG: tpd:Teth39_0754 NifU domain-containing protein.
 
 0.768
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.