Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ADH61249.1Hypothetical protein; KEGG: cbe:Cbei_0503 S-layer domain-containing protein. (493 aa)    
Predicted Functional Partners:
ADH61248.1
KEGG: tpd:Teth39_0755 hypothetical protein.
       0.780
cobB
Silent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
       0.715
ADH61250.1
PFAM: nitrogen-fixing NifU domain protein; KEGG: tpd:Teth39_0754 NifU domain-containing protein.
       0.529
ADH61246.1
KEGG: tpd:Teth39_0757 cold-shock DNA-binding domain-containing protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein.
       0.523
ADH61251.1
KEGG: tex:Teth514_2068 putative GAF sensor protein; PFAM: GAF domain protein; SMART: GAF domain protein.
       0.429
hslO
Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
       0.417
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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