Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH61261.1PFAM: protein of unknown function DUF34; KEGG: tpd:Teth39_0741 hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. (371 aa)    
Predicted Functional Partners:
ADH61262.1
PFAM: protein of unknown function DUF633; KEGG: tex:Teth514_1316 hypothetical protein.
  
 0.991
ADH60190.1
KEGG: tex:Teth514_0304 putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II.
  
  
 0.751
hisC
KEGG: tpd:Teth39_0517 histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
 0.751
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
   
 0.672
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
     
 0.649
ADH61265.1
TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: tpd:Teth39_0737 deoxyguanosinetriphosphate triphosphohydrolase-like protein; SMART: metal-dependent phosphohydrolase HD region; Belongs to the dGTPase family. Type 2 subfamily.
       0.561
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
 
 
   0.556
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
    0.541
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.498
ADH61893.1
PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: tpd:Teth39_0098 peptidase M1, membrane alanine aminopeptidase.
 
    0.497
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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