Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADH61262.1PFAM: protein of unknown function DUF633; KEGG: tex:Teth514_1316 hypothetical protein. (234 aa)    
Predicted Functional Partners:
ADH61261.1
PFAM: protein of unknown function DUF34; KEGG: tpd:Teth39_0741 hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
  
 0.991
ADH60815.1
PFAM: protein of unknown function DUF965; KEGG: tpd:Teth39_1053 hypothetical protein; Belongs to the UPF0297 family.
  
     0.739
ADH61087.1
PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: tpd:Teth39_1330 fibronectin-binding A domain-containing protein.
 
     0.639
ADH60791.1
KEGG: tpd:Teth39_1021 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
  
     0.608
ADH61022.1
Putative helix-turn-helix protein YlxM/p13 family protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
     0.591
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
       0.579
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
  
     0.576
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
       0.572
ADH61924.1
Phosphoesterase RecJ domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
  
     0.541
ADH61930.1
PFAM: protein of unknown function DUF951; KEGG: tpd:Teth39_2276 hypothetical protein.
  
     0.527
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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