Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH61265.1TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: tpd:Teth39_0737 deoxyguanosinetriphosphate triphosphohydrolase-like protein; SMART: metal-dependent phosphohydrolase HD region; Belongs to the dGTPase family. Type 2 subfamily. (333 aa)    
Predicted Functional Partners:
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
 
  
  0.917
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 
  0.903
ADH60156.1
5'-Nucleotidase domain protein; KEGG: tpd:Teth39_1938 5'-nucleotidase, 2',3'-cyclic-nucleotide 2'-phosphodiesterase; PFAM: 5'-Nucleotidase domain protein; SH3 type 3 domain protein; metallophosphoesterase; SMART: SH3 domain protein; Capsule synthesis protein, CapA.
    
  0.900
deoD
KEGG: tpd:Teth39_0743 purine nucleoside phosphorylase; TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1.
     
  0.900
ADH61357.1
KEGG: tpd:Teth39_0653 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein.
     
  0.900
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
     
 0.667
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
       0.639
ADH61261.1
PFAM: protein of unknown function DUF34; KEGG: tpd:Teth39_0741 hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
       0.561
ADH61266.1
Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
       0.559
ADH61262.1
PFAM: protein of unknown function DUF633; KEGG: tex:Teth514_1316 hypothetical protein.
       0.481
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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