Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH61276.1Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: tpd:Teth39_0726 ferric uptake regulator family protein; Belongs to the Fur family. (135 aa)    
Predicted Functional Partners:
ADH60090.1
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
 
  
 0.614
ADH60774.1
PFAM: CoA-binding domain protein; KEGG: tpd:Teth39_1005 CoA-binding domain-containing protein.
  
    0.574
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.538
ADH61275.1
KEGG: tpd:Teth39_0727 Cof-like hydrolase; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; Sucrose-phosphate phosphatase subfamily; PFAM: Haloacid dehalogenase domain protein hydrolase type 3.
       0.526
ADH61274.1
PFAM: acylphosphatase; KEGG: tpd:Teth39_0728 acylphosphatase.
     
 0.502
ADH60092.1
KEGG: tpd:Teth39_2004 hypothetical protein.
  
    0.493
ADH61273.1
KEGG: tpd:Teth39_0729 RNA polymerase, sigma 54 subunit, RpoN; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor.
  
  
 0.447
ADH60169.1
KEGG: tpd:Teth39_1925 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
  
  
 0.422
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.415
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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