Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (213 aa)    
Predicted Functional Partners:
ADH60843.1
KEGG: tex:Teth514_1518 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease family 2.
  
 
 0.854
rnfE
Electron transport complex, RnfABCDGE type, E subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
 
  
 0.841
ADH61279.1
PFAM: domain of unknown function DUF1730; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tpd:Teth39_0723 hypothetical protein.
       0.836
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 
 0.819
ADH60516.1
PFAM: PP-loop domain protein; KEGG: tpd:Teth39_1540 ExsB family protein.
 
    0.735
ADH61277.1
PFAM: VanW family protein; G5 domain protein; KEGG: tpd:Teth39_0725 VanW family protein.
       0.660
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.655
ADH61771.1
PHP domain protein; KEGG: tex:Teth514_0650 phosphotransferase domain-containing protein; PFAM: PHP domain protein; SMART: DNA polymerase X; phosphoesterase PHP domain protein; Helix-hairpin-helix DNA-binding class 1.
     
 0.599
rnfG
Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.
  
  
 0.595
ADH60988.1
CheC, inhibitor of MCP methylation / FliN fusion protein; KEGG: tex:Teth514_1680 flagellar motor switch protein; TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein.
   
   0.514
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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