Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (321 aa)    
Predicted Functional Partners:
ADH61326.1
Pyruvate kinase; KEGG: tex:Teth514_1195 pyruvate kinase., pyruvate, water dikinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family.
 
 
 0.999
pgi
KEGG: tpd:Teth39_0694 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); Belongs to the GPI family.
  
 0.982
ADH59961.1
TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; KEGG: tpd:Teth39_2115 fructose-1,6-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II.
 
 
 0.963
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 0.939
ADH61832.1
1-phosphofructokinase; KEGG: tex:Teth514_0576 1-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
     
 0.936
mtlD
PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: tex:Teth514_0271 mannitol-1-phosphate 5-dehydrogenase.
 
  
 0.923
ADH61377.1
PFAM: PfkB domain protein; KEGG: tex:Teth514_1119 ribokinase-like domain-containing protein; Belongs to the carbohydrate kinase PfkB family.
  
 0.918
ADH61259.1
TIGRFAM: mannose-6-phosphate isomerase, class I; KEGG: tex:Teth514_1319 mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I.
    
 0.913
ADH61520.1
KEGG: tex:Teth514_0969 transketolase, central region; PFAM: Transketolase central region; Transketolase domain protein; SMART: Transketolase central region.
    
  0.903
ADH61521.1
PFAM: Transketolase domain protein; KEGG: tpd:Teth39_0491 transketolase domain-containing protein.
    
 0.903
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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