Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH61343.1Conserved hypothetical protein; Displays ATPase and GTPase activities. (284 aa)    
Predicted Functional Partners:
ADH61342.1
Protein of unknown function UPF0052 and CofD; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
  
  
 0.983
ADH60622.1
Ribonuclease, Rne/Rng family; KEGG: tpd:Teth39_1439 ribonuclease; TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; RNA binding S1 domain protein.
 
 
 
 0.835
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
     
 0.826
ADH61344.1
PHP domain protein; KEGG: tpd:Teth39_0665 phosphotransferase domain-containing protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein.
       0.788
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
 
  
 0.717
hpf
Sigma 54 modulation protein/ribosomal protein S30EA; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
 
  
 0.546
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
   
 0.531
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.479
ADH61346.1
Manually curated; KEGG: tpd:Teth39_0663 hypothetical protein.
       0.469
ADH59994.1
KEGG: tpd:Teth39_2082 PTS system transcriptional activator; PFAM: sigma-54 factor interaction domain-containing protein; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PTS system fructose subfamily IIA component; PRD domain protein; SMART: AAA ATPase.
  
    0.466
Your Current Organism:
Thermoanaerobacter mathranii
NCBI taxonomy Id: 583358
Other names: T. mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii A3, Thermoanaerobacter mathranii subsp. mathranii DSM 11426, Thermoanaerobacter mathranii subsp. mathranii str. A3, Thermoanaerobacter mathranii subsp. mathranii strain A3
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